Recently, a China-U.S team reviewed the synthesis of carbon-based hybrid nanogels and their applications in biomedical areas.
Responsive nanogels are playing an increasingly important role in medical areas due to their porous structures, large surface area, good biocompatibility and responsiveness to internal and/or external chemico-physical stimuli.
Through introducing carbon nanomaterials during the preparation of responsive nanogels, the resulting hybrid nanogels are expected to integrate the unique electro-optical properties of carbon nanomaterials with the merits of nanogels into a single hybrid nanogel system for improvement of their applications in nanomedicine.
In this review article, the team fully summarizes the synthesis of carbon-based hybrid nanogels containing fullerene, graphene, carbon nanotubes, carbon nanoparticless, carbon dots and nanodiamond, and discusses their structural characteristics, combined functions and synergistic properties.
Furthermore, the team claims the potential biomedical applications of carbon-based hybrid nanogels as biosensor, bioimaging agent, responsive drug carriers and therapeutic agents, and addresses the current issues and further perspectives of carbon-based hybrid nanogel.
The related results were published in Chemical Society Reviews entitled Carbon-based hybrid nanogels: a synergistic nanoplatform for combined biosensing, bioimaging, and responsive drug delivery.
The joint research team was led by Prof. WANG Hui from High Magnetic Field Laboratory of Chinese Academy of Sciences, Prof. CHEN Qianwang from University of Science and Technology of China and Prof. ZHOU Shuiqin from The College of Staten Island of The City University of New York.
The work was supported by the National Natural Science Foundation of China, the American diabetes association, and the Chinese Academy of Sciences.
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Carbon-based hybrid nanogels for biomedical applications (Image by WANG Hui) |
