Our team is focusing on the signaling transduction pathway mediated translational medical research that aims to answer the clinically raised fundamental pathological questions from the basic research perspective and fulfill unmet medical needs from drug discovery point of view. To do this, we integrate multiple disciplines such as Chemistry, Biochemistry, Medicinal Chemistry, Chemical Biology, Structural Biology, Molecule Biology, Pharmacology, Bioinformatics and Pathology into the whole chain of drug discovery pipeline by application of Structural Based Drug design, Computer Aided Drug Design, NMR Mediated Fragment Based Drug Design, High Throughput Drug Screening and Combination Drug Regime Design technologies or concepts.